Mutagenicity of niclosamide and N-substituted phenylbenzamides using the Ames assay.

The values shown represent the mean number of revertant colonies in the presence and absence of exogenous metabolic activation (Aroclor 1254 induced rat liver S9) from 3 replicate wells. The positive control chemicals were 2-Aminoanthracene (2-AA) for all S9 activation experiments, 2-nitrofluorene (2-NF 2) for TA98, SA for TA100 and TA1535, ICR-191 for TA-1537 and MNNG for WP2 uvrA. * indicates compounds that exhibit statistically significant increases in mean revertant colonies (p<0.05) as indicated by the Ames assay.