Anti-trypanosomal activities of sponge associated actinomycetes.

NIAID Data Ecosystem2026-03-09 收录

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Anti-trypanosomal activities of sponge associated actinomycetes.

创建时间：

2015-09-25

Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs

抗锥虫药物

黄酮醇衍生物

Flavonoids represent a potential source of new antitrypanosomatidic leads. Starting from a library of natural products, we combined target-based screening on pteridine reductase 1 with phenotypic scre

NIAID Data Ecosystem60

Crystal structure of Trypanosoma cruzi CYP51 bound to the inhibitor (R)-N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-4-(4-(2,4-difluorophenyl)piperazin-1-yl)-2-fluorobenzamide.

抗寄生虫药物靶点结构

抗锥虫药物

Crystal structure of Trypanosoma cruzi CYP51 bound to the inhibitor (R)-N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-4-(4-(2,4-difluorophenyl)piperazin-1-yl)-2-fluorobenzamide. Descrip

Protein Data Bank Japan2023-12-20 更新30

Antitrypanosomal Activity of a New Triazine Derivative, SIPI 1029, In Vitro and in Model Infections

抗锥虫药物

锥虫病药效学

A recently developed diaminotriazine derivative [O,O′-bis(1,2-dihydro-2,2-tetramethylene-4,6-diamino-S-triazin-1-yl)-1,6-hexanediol dihydrochloride; T-46; SIPI 1029] was examined for activity against

PubMed Central10

Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs

抗锥虫药物

黄酮醇衍生物

NIAID Data Ecosystem60

Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs

兽药生产

抗锥虫药物

African trypanosomes cause disease in both humans and animals. The livestock disease primarily caused by Trypanosoma congolense, T. vivax or T. brucei, in cattle is known as nagana and, is responsible

NIAID Data Ecosystem20

Anti-trypanosomal activities of sponge associated actinomycetes.

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