Supplementary Info – Endothelial glycocalyx permeability for nanoscale solutes

1.1 Van der Waals interactions 1.2 Hydrodynamic model details Figure 1. (A) Scheme of multi-bead monomer representation. Left panel demonstrates the placement of the virtual particles around the real ones. Central panel is an analogue with real spring-bonded particles. Right panel illustrates the effective hydrodynamic radius of the monomer for the model. (B) Comparison of polymer brush with and without the additional particles Figure 2. NP density distributions at various heights z from the channel walls. Here we compared the distributions in xy-plane between the bush-like model (left panel) and brush-like model (right panel) for the NPs of size R = 5 nm. Figure 3. NP density distributions at various heights z from the channel walls. Here we compared the distributions in xy-plane between the bush-like model (left panel) and brush-like model (right panel) for the NPs of size R = 15 nm.