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Functional Oocytes Derived from Granulosa Cells

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NIAID Data Ecosystem2026-04-25 收录
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Generation of genome stable and functional oocytes would hold great potential in fertility preservation and restoration of ovarian function. We examined genomic stability by Exome-seq analysis of gPSC lines (Chemical-induced iPS from granulosa cells ), and compared with high-quality ESC line, OG4-ESCs. Furthermore, to assess the genomic stability during PGCLC induction, we performed Exome-seq between E12.5 PGCs and gPSC4/15-PGCLCs and between Wild-type/natural GV oocytes and GV oocytes derived from gPSC-pups.

创建时间:
2019-10-01
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