Environmental and Molecular Regulation of Diapause Formation in a Scyphozoan Jellyfish

Understanding the mechanisms underlying diapause formation is crucial for gaining insight into adaptive survival strategies across various species.In this study, we explored the cellular and molecular basis of diapause formation using single-cell RNA sequencing. In addition, we mapped the single-cell atlas of diapausing podocysts, identifying cell types involved in metabolism, environmental sensing, defence, and development, which may collectively contribute to the long-term survival and regulated excystment of diapausing podocysts.