To elucidate the dependence of B-ALL cells on PTEN we analysed the transcriptional changes upon inducible Pten KO in BCR-ABL1 transformed pre-B cells. Transciptome analysis of Pten+/+ and Pten-/- cell
RNA-sequencing for a cohort of B-ALL samples : 5 Down Syndrome (DS), 16 Hyperdiploid (HeH), 6 iAMP21, 9 other. RNA-sequencing for B-cell progenitors from 3 healthy. It also contains RNA-sequencing
Here, we demonstrate that ZNF217 plays an oncogenic role in B-ALL. To investigate the underlying mechanisms and pinpoint potential downstream targets that contribute to ZNF217's oncogenic role, we co