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Crystal structure of phosphorylated RET V804M tyrosine kinase domain complexed with PDD00018366

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Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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Crystal structure of phosphorylated RET V804M tyrosine kinase domain complexed with PDD00018366 Descriptor: 4-[5-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-3-yl]benzamide, FORMIC ACID, Proto-oncogene tyrosine-protein kinase receptor Ret Authors: Burschowsky, D, Seewooruthun, C, Bayliss, R, Carr, M.D, Echalier, A, Jordan, A.M. Deposit date: 2018-11-19 Release date: 2020-03-11 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RETV804MKinase. Acs Med.Chem.Lett., 11, 2020

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2018-11-19
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