five

Kynurenine Aminotransferase II Inhibitors

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Protein Data Bank Japan2023-09-13 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4geb
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资源简介:
Kynurenine Aminotransferase II Inhibitors Descriptor: (5-hydroxy-4-{[(7-hydroxy-6-oxo-2-phenyl-6,7-dihydro-2H-pyrazolo[3,4-b]pyridin-5-yl)amino]methyl}-6-methylpyridin-3-yl)methyl dihydrogen phosphate, Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial, ... Authors: Pandit, J. Deposit date: 2012-08-01 Release date: 2013-03-20 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.15 Å) Cite: PF-04859989 as a template for structure-based drug design: identification of new pyrazole series of irreversible KAT II inhibitors with improved lipophilic efficiency. Bioorg.Med.Chem.Lett., 23, 2013
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2012-08-01
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