c-Fos bound proximal regions are depleted of AP-1 motifs.

Proportion of AP-1 motif occurrence in proximal and distal genomic ChIP-seq intervals bound by c-Fos, but not by NF-YB are shown. Proximal (p) and distal (d) genomic intervals targeted by c-Fos, but not by NF-YB (column c-Fos of Table 1) differ significantly in the occurrence of AP-1 motifs detected by an AP-1 PWM (Fig 1); AP-1+: number of intervals with, AP-1−: without a detectable AP-1 motif. In the last column the Fisher’s Exact Odds Ratios (OR, bold) and the corresponding P-values (in parentheses) are given.