Dissecting Gene Expression Changes Accompanying a Euploid-Aneuploid Phenotypic Switch

Purpose:To dissect the mechanisms underlying altered gene expression in aneuploids, we measured transcript abundance in colonies of haploid yeast strain F45 and derived strains, including strains disomic for chromosomes XV and XVI, using RNA-seq研究目的：为解析非整倍体（aneuploid）基因表达改变的潜在机制，我们采用RNA测序（RNA-seq）技术，对单倍体酵母菌株F45及其衍生菌株（包含XV号与XVI号染色体二体菌株）的菌落转录本丰度开展了检测。