Catalytic Asymmetric Diaziridination
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https://figshare.com/articles/dataset/Catalytic_Asymmetric_Diaziridination/2430778
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资源简介:
The first catalytic
enantio- and diastereoselective synthesis of
diaziridines is presented. Aziridination of N-tosyl
aldimines applying modified hydroxylamine under asymmetric phase-transfer
catalysis furnished optically active diaziridines. The diaziridines
are formed as a single diastereomer in up to 96% ee, containing two
orthogonal N-protecting groups, which can be deprotected
selectively.
创建时间:
2016-02-19



