Chromatin state in RA or LE540-treated human CD4+ T cells
收藏NIAID Data Ecosystem2026-03-13 收录
下载链接：
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE137714
下载链接
链接失效反馈官方服务：
资源简介：
Retinoic Acid (RA)-treated T cells show effector-like properties such as down-regulation of CD62L, weak proliferation, low survival in vitro/in vivo. In contrast, LE540 (RAR antagonist)-treated T cells show memory-like properties. In this study, using ChIP-seq, we investigated change of chromatin state induced by RAR signaling in T cells. We found that RAR signaling comprehensively induces repressive chromatin states and deletes the memory T cell profile. Examination of 2 different histone modifications in 3 cell types.
创建时间：
2022-01-01
