Mechanistic Insights into GPCR-Gαβγ Complex Initiating Nucleotide Exchange

NIAID Data Ecosystem2026-05-01 收录

GPCR信号转导

G蛋白核苷酸交换

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https://digitalcommonsdata.usf.edu/datasets/j4zssvyf98 数据链接链接失效反馈

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Raw data for Figure 1B Raw data for Figures 2A-2G Uncut Native-PAGE for Figure S2B Uncut SDS-PAGE for FPLC fractions

创建时间：

2024-04-01

RNA sequencing to determine the contribution of kinase receptor transactivation to G protein coupled receptor signalling in vascular smooth muscle cells. Homo sapiens

GPCR信号转导

激酶受体反式激活

G protein coupled receptor (GPCR) signalling covers three major mechanisms. GPCR agonist engagement allows for the G proteins to bind to the receptor leading to a classical downstream signalling casca

NIAID Data Ecosystem60

Additional file 6 of Bayesian analysis of dynamic phosphoproteomic data identifies protein kinases mediating GPCR responses

磷酸化网络

GPCR信号转导

Additional file 5: Table S5. Nodes and edges for the causal map of vasopressin effects in IMCD. Source nodes were mapped to Target nodes based on literature searches and data from this paper. Informat

Figshare2022-06-05 更新50

Structure of beta-arrestin1 in complex with a phosphopeptide corresponding to the human C-X-C chemokine receptor type 4, CXCR4 (Local refine)

GPCR信号转导

蛋白质结构解析

Structure of beta-arrestin1 in complex with a phosphopeptide corresponding to the human C-X-C chemokine receptor type 4, CXCR4 (Local refine) Descriptor: Beta-arrestin-1, C-X-C chemokine receptor type

Protein Data Bank Japan2024-11-13 更新40

S-nitrosylation is essential for β2AR desensitization and experimental asthma

GPCR信号转导

哮喘分子机制

Raw image files for study. The β2-adrenergic receptor (β2AR), a prototypic G protein-coupled receptor (GPCR), is a powerful driver of bronchorelaxation, but the effectiveness of β-agonist drugs in ast

NIAID Data Ecosystem60

Agnathan VIP, PACAP and Their Receptors: Ancestral Origins of Today's Highly Diversified Forms

神经肽进化分析

GPCR信号转导

VIP and PACAP are pleiotropic peptides belonging to the secretin superfamily of brain-gut peptides and interact specifically with three receptors (VPAC1, PAC1 and VPAC2) from the class II B G protein-

NIAID Data Ecosystem50

Mechanistic Insights into GPCR-Gαβγ Complex Initiating Nucleotide Exchange

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