Rat protein farnesyltransferase complexed with FPP and BMS-214662
收藏Protein Data Bank Japan2023-08-23 更新2026-03-21 收录
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Rat protein farnesyltransferase complexed with FPP and BMS-214662 Descriptor: 3-BENZYL-1-(1H-IMIDAZOL-4-YLMETHYL)-4-(THIEN-2-YLSULFONYL)-2,3,4,5-TETRAHYDRO-1H-1,4-BENZODIAZEPINE-7-CARBONITRILE, ACETIC ACID, FARNESYL DIPHOSPHATE, ... Authors: Reid, T.S, Beese, L.S. Deposit date: 2004-02-06 Release date: 2004-06-08 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal Structures of the Anticancer Clinical Candidates R115777 (Tipifarnib) and BMS-214662 Complexed with Protein Farnesyltransferase Suggest a Mechanism of FTI Selectivity. Biochemistry, 43, 2004
创建时间：
2004-02-06
