Assessment of genes identified by Schimenti and Handel (2018)
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Following our systematic gene search and assessment using Online Mendelian Inheritance of Man (OMIM), an additional 19 genes from a review (Schimenti and Handel., 2018) were evaluated for suitability. One gene, Capza3 (highlighted in grey), passed our gene requirements for fertility targeted gene drives, and was subsequently added to our male candidate gene list. Gene name, OMIM access number, KO (KO) phenotype, evidence of sex bias effect, description of gene expression pattern and reference to mouse KO model are shown.
创建时间：
2021-01-03
