Synthesis of Bis-pyrrolizidine-Fused Dispiro-oxindole Analogues of Curcumin via One-Pot Azomethine Ylide Cycloaddition: Experimental and Computational Approach toward Regio- and Diastereoselection
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https://figshare.com/articles/dataset/Synthesis_of_Bis_pyrrolizidine_Fused_Dispiro_oxindole_Analogues_of_Curcumin_via_One_Pot_Azomethine_Ylide_Cycloaddition_Experimental_and_Computational_Approach_toward_Regio_and_Diastereoselection/2130352
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资源简介：
Curcumin
has been transformed to racemic curcuminoids via an azomethine
ylide cycloaddition reaction using isatin/acenaphthoquinone and proline
as the reagents. The products were characterized by extensive 1D/2D
NMR analysis and single-crystal X-ray crystallographic studies. The
enantiomers of one racemic product were separated by HPLC on a Chiralcel
OD-H column and were indeed confirmed by the CD spectra of the separated
enantiomers.
创建时间：
2016-02-13
