Small RNA GcvB regulates oxidative stress response of Escherichia coli through its control of OxyR

We investigated the gene expression changed in the NCM3722 wild-type and gcvB deletion strains grown in glucose minimal medium, aiming to find novel target genes controlled by small RNA GcvB. In total, five differentially expressed genes (DEGs) were identified by Illumina sequencing using a cutoff with fold change>2 and q-value<0.01. Following physiological and molecular studies identified that the physiological roles of GcvB were beyond amino acids transportation and it regulates oxdative stress response of Escherichia coli through its control of OxyR. Study gene expression in E. coli NCM3722 wild-type and gcvB deletion strains grown in glucose minimal medium.