Supporting tables.

Table S1: Information on donors used in this study. Table S2: Differentially expressed genes (DEGs) in CSE-treated bronchospheres versus control. Table S3: Up- and down-regulated DEGs calculated for each smokers vs non-smokers comparison. Table S4: Gene set enrichment analysis (GSEA) of CSE-treated bronchospheres data in 14 smoking signatures comparisons. Table S5: Gene set enrichment analysis (GSEA) of CSE-treated bronchospheres pooled comparison data in KEGG pathways database, Hallmark MSigDB, and GO Biological Process. Table S6: Description of the 7 different comparisons generated from 3 separate datasets that were used for GSEA in Fig 2. Table S7: Compounds used in the primary screen mechanism of action (MoA) diversity deck. Table S8: Results of the primary screen that were plotted in Fig 3B and 3C. (XLSX)