Sociodemographics, lifestyle and clinical chacteristics for treatment-naïve patients in CARMS 5 with or without fibrosis.

Abbreviations used: SD = standard deviation, IQR = interquartile range.
Data are expressed as mean and standard deviation for continous variables (p-25-hydroxyvitamin D and body mass index) and as median and interquartile range for categorical variables (age, supplement use, physical activity, smoking habits and alcohol intake). There was a significant difference in p-25-hydroxyvitamin D between patients with fibrosis and patients without fibrosis (p<0.001). Note that patients with neovascular AMD who were receiving anti-vascular endothelial growth factors in the past or present were excluded from this analysis. Body mass index data missing for 2 patients with subretinal fibrosis and 1 patient without subretinal fibrosis.
*Only patients with active CNV type 1 or 2 on fluorescein angiography (data not analyzed using multiple logistic regression since only 34 patients had active classic/occult CNV). The type of choroidal neovascularization was not included in the multiple logistic regression analysis as not all patients had active CNV, and best corrected visual acuity was not included because it is not the cause of subretinal fibrosis, but a result of it.