Complement factor D in complex with the inhibitor (S)-Pyrrolidine-1,2-dicarboxylic acid 1-[(1-methyl-1H-indol-3-yl)-amide] 2-[(3-trifluoromethoxy-phenyl)-amide]
收藏Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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Complement factor D in complex with the inhibitor (S)-Pyrrolidine-1,2-dicarboxylic acid 1-[(1-methyl-1H-indol-3-yl)-amide] 2-[(3-trifluoromethoxy-phenyl)-amide] Descriptor: (2~{S})-~{N}1-(1-methylindol-3-yl)-~{N}2-[3-(trifluoromethyloxy)phenyl]pyrrolidine-1,2-dicarboxamide, Complement factor D, GLYCEROL Authors: Mac Sweeney, A, Ostermann, N. Deposit date: 2017-02-28 Release date: 2018-03-21 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.17 Å) Cite: Discovery of Highly Potent and Selective Small-Molecule Reversible Factor D Inhibitors Demonstrating Alternative Complement Pathway Inhibition in Vivo. J.Med.Chem., 60, 2017
创建时间：
2017-02-28
