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Adverse Outcome Pathway on deposition of energy leading to lung cancer

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Organisation for Economic Co-operation and Development2026-04-11 收录
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https://www.oecd.org/en/publications/adverse-outcome-pathway-on-deposition-of-energy-leading-to-lung-cancer_a8f262c2-en.html
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The present Adverse Outcome Pathway (AOP) describes the linkage between lung cancer initiated from the Deposition of Energy (DoE) into a cell by a prototypic stressor such as radon gas. The multiple ionization events from DoE can directly break DNA double strands and initiate the activation of repair machinery through non-homologous end joining,...
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