Evaluation of porcine fecal microbiomes after exposure to ceftriaxone
收藏NIAID Data Ecosystem2026-03-09 收录
下载链接:
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA352989
下载链接
链接失效反馈官方服务:
资源简介:
A porcine model of antibiotic-mediated gut microbiome dysbiosis was developed and used to evaluate the protective effect of an intestinal antibiotic degradation strategy on the gut microflora. An engineered beta-lactamase enzyme was formulated for oral delivery and evaluated in pigs receiving ceftriaxone. The microbiomes of pigs receiving ceftriaxone alone or ceftriaxone and the beta-lactamase were compared using whole genome shotgun metagenomics analyses of the fecal DNA.
创建时间:
2016-11-09



