Gene expression profile at single nuclei level of microglia from brain hippocampus
收藏Alliance of Genome Resources2026-08-01 收录
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We used single nuclei RNA sequencing (snRNA-seq) to analyze the diversity of microglia depending on the presence or not of 1) tau pathology (P301S), 2) TREM2, 3) APOE4 The hippocampi of three mice per experimental group were dissociated and the cell nuclei were labelled with the myeloid lineage-determining transcription factor PU.1 and sorted for subsequent single nuclei RNA-seq analysis
