Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain bound with 7-(3-aminomethyl)phenyl-6-fluoro-4-methylquinoin-2-amine

Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain bound with 7-(3-aminomethyl)phenyl-6-fluoro-4-methylquinoin-2-amine Descriptor: (7P)-7-[3-(aminomethyl)phenyl]-6-fluoro-4-methylquinolin-2-amine, 5,6,7,8-TETRAHYDROBIOPTERIN, GLYCEROL, ... Authors: Li, H, Poulos, T.L. Deposit date: 2025-01-22 Release date: 2025-12-03 Last modified: 2026-08-12 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Enhancement of Potency and Selectivity of 2-Aminoquinoline-Based Human Neuronal Nitric Oxide Synthase Inhibitors. J.Med.Chem., 69, 2026