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The complex crystal structure of LCK with a probe molecule w259

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Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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The complex crystal structure of LCK with a probe molecule w259 Descriptor: 3-[7-[(3-hydroxyphenyl)amino]pyrazolo[1,5-a]pyrimidin-2-yl]-N-(1-hydroxy-2,2,6,6-tetramethyl-piperidin-4-yl)benzamide, CALCIUM ION, Proto-oncogene tyrosine-protein kinase LCK, ... Authors: Xu, Z.B, Moy, F.J, Kelleher, K, Mosyak, L, Protein Structure Factory (PSF) Deposit date: 2009-12-04 Release date: 2010-06-23 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.37 Å) Cite: Novel synthesis and structural characterization of a high-affinity paramagnetic kinase probe for the identification of non-ATP site binders by nuclear magnetic resonance. J.Med.Chem., 53, 2010

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2009-12-04
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