Methionine metabolism leading to sulfur amino acids and related disorders

This pathway visualises the conversion of methionine to inorganic sulphates (involving the formation of homocysteine, a toxic intermediate also related to MTHFR deficiency [https://www.wikipathways.org/index.php/Pathway:WP4288]). Methionine, an essential amino acid, is taken in from diet and can be created from breaking down proteins. This pathway was inspired by Chapter 3 of the book of Blau (ISBN 3642403360 (978-3642403361)).

本路径图展示了蛋氨酸向无机硫酸盐的转化过程（涉及同型半胱氨酸的形成，该有毒中间体亦与MTHFR缺乏症相关[https://www.wikipathways.org/index.php/Pathway:WP4288]）。蛋氨酸作为一种必需氨基酸，可通过饮食摄取或由蛋白质分解产生。此路径图灵感来源于Blau所著书籍的第三章（ISBN 3642403360（978-3642403361））。