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资源简介：
Data used within the publication: En Masse Evaluation of RNA Guides (EMERGe) for ADARs
应用场景：
创建时间：
2024-03-28
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Recruiting Endogenous ADARs with Antisense Oligonucleotides to Reprogram the Transcriptome. Recruiting Endogenous ADARs with Antisense Oligonucleotides to Reprogram the Transcriptome
Huge efforts are made to engineer safe and efficient genome editing tools. An alternative might be the harnessing of ADAR-mediated RNA editing. We now present the engineering of chemically optimized a
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Programmable RNA Editing with Circular ADAR-recruiting RNAs
Leveraging endogenous ADAR for programmable editing on RNA has great potential for therapeutic and biomedical research. Here we use circular ADAR recruiting RNA to achieve precise and long-lasting edi
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Zfr regulates ADAR-mediated RNA editing in mouse primary neurons
We used RNA-seq of mouse primary cortical neurons transfected with control shRNAs or shRNAs targeting ADAR1, ADAR2, or Zfr to test for A-to-I RNA editing level differences between control and knockdow
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Adenosine deaminases that act on RNA induce reproducible changes in abundance and sequence of embryonic miRNAs
We used transgenic mouse embryos that are deficient in the two enzymatically active RNA editing enzymes ADAR1 and ADAR2 to compare relative frequencies but also sequence composition of mature miRNAs i
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Human ADAR -targeting guide RNA editing and protein loss kinetics data.
Human ADAR-targeting guide RNA editing and protein loss kinetics data.
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