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Crystal structure of TRIM24 PHD-bromodomain complexed with 1-methyl-5-(2-methyl-1 3-thiazol-4-yl)-2 3-dihydro-1H-indol-2-one (1)

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Protein Data Bank Japan2023-09-27 更新2026-03-21 收录
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Crystal structure of TRIM24 PHD-bromodomain complexed with 1-methyl-5-(2-methyl-1 3-thiazol-4-yl)-2 3-dihydro-1H-indol-2-one (1) Descriptor: 1-methyl-5-(2-methyl-1,3-thiazol-4-yl)-1,3-dihydro-2H-indol-2-one, SULFATE ION, Transcription intermediary factor 1-alpha, ... Authors: Poncet-Montange, G, Palmer, W, Jones, P. Deposit date: 2015-02-17 Release date: 2015-06-24 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor. J.Med.Chem., 59, 2016
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2015-02-17
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