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Chromatin plays roles in processes governed by different time scales
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High resolution chromatin dynamics during a yeast stress response
Covalent histone modifications are highly conserved and play multiple roles in eukaryotic transcription regulation. Because of extensive crosstalk between transcriptional processes and histone modific
NIAID Data Ecosystem70
Chromatin states and genomic organization impact local replication features and timing [ChIP-seq]
Replication timing (RT) control is linked to histone modifications (HMs) and genome architecture. However, HM landscape across cell cycle and its relationship with RT and chromatin modifiers have not
NIAID Data Ecosystem40
Leo1 is essential for dynamic regulation of heterochromatin and gene expression during cellular quiescence [RNA-Seq]. Leo1 is essential for dynamic regulation of heterochromatin and gene expression during cellular quiescence [RNA-Seq]
Cellular quiescence is a reversible differentiation state when cells are changing the gene expression programme to reduce metabolic functions and adapt to a new cellular environment. The epigenetic ch
NIAID Data Ecosystem30
CRISPR-mediated multiplexed live cell imaging of nonrepetitive genomic loci with one guide RNA per locus (Imaging Data)
Three-dimensional (3D) structures of the genome are dynamic, heterogeneous and functionally important. Live cell imaging has become the leading method for chromatin dynamics tracking. However, existin
DataCite Commons2022-03-07 更新50
Nucleosome and histone modification during yeast meiosis
During meiosis to form gametes or spores, chromosomes undergo dramatic compaction, which might be expected to result in tighter nucleosome packing. Here we investigate the impact of meiotic genome co
NIAID Data Ecosystem40
