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资源简介：
The complete rag1 dataset (22 sequences)
应用场景：
创建时间：
2014-01-01
相关数据集
The RAG-HMG1 Complex Enforces the 12/23 Rule of V(D)J Recombination Specifically at the Double-Hairpin Formation Step
A central unanswered question concerning the initial phases of V(D)J recombination has been at which step the 12/23 rule applies. This rule, which governs which variable (V), diversity (D), and joinin
PubMed Central70
NUDCD3 deficiency disrupts V(D)J recombination to cause SCID/Omenn syndrome
Inborn errors of T cell development present a pediatric emergency in which timely curative therapy is informed by molecular diagnosis. In 9 affected patients across 3 consanguineous kindreds, we detec
NIAID Data Ecosystem40
Jk DNA GAGA MOTIFS ARE REQUIRED FOR LOCAL NUCLEOSOME REMODELING AND Vk-Jk RECOMBINATION [RNA-Seq]
Immunoreceptor gene recombination requires complementary 12 bp and 23 bp recombination signal sequences (RSSs). In addition, the RSSs that assemble the RAG proteins, recombination centers, must be acc
NIAID Data Ecosystem20
The Nicking Step in V(D)J Recombination Is Independent of Synapsis: Implications for the Immune Repertoire
In all of the transposition reactions that have been characterized thus far, synapsis of two transposon ends is required before any catalytic steps (strand nicking or strand transfer) occur. In V(D)J
PubMed Central70
J region use by V14: comparison between experimental and simulation data.
*Frequencies of rearrangements of V14 genes were calculated from Figure 2 in Aude-Garcia et al.[10], for the combinations with three J panels, corresponding to series of J genes scattered along the J
NIAID Data Ecosystem30
