five

MtDNA variation in different tissues

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/ERP004896
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To investigate the mtDNA variation in different tissues in human, we sequenced 12 tissues from 152 individuals (from autopsy). MtDNA was enriched by in-solution capture method (Maricic et al. PLoS ONE 5(11): e14004). We have successfully sequenced 1684 samples, with average coverage of 3458X (46X-36444X). 12 tissues include: blood(BL), cerebellum(CEL), cerebrum(CER), cortex(CO), kidney(KI), large intestine(LI), liver(LV), myocardial muscle(MM), ovary(OV), skeletal muscle(SM), skin(SK), small intestine(SI). All samples were ligated with specific barcode and sequenced in one Illumina HiSeq 2000 run (95bp paired-end).
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2021-02-04
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