AimsThe goal of our study is to assess the contribution of KIF6 Trp719Arg to both the risk of CHD and the efficacy of statin therapy in CHD patients. Methods and ResultsMeta-analysis of 8 prospective

NIAID Data Ecosystem20

Association results for 2 candidate CHD risk loci in stage 1, stage 2 and combined data.

冠心病遗传关联

遗传流行病学

P values and OR (95%CI) were comparing the control group with CHD group under additive model; HWE-P: P value of Hardy–Weinberg equilibrium test for controls.

NIAID Data Ecosystem20

The association analysis for number of affected vessels using rs1333049 as predictors in a linear regression model in CAD patients and subgroups.

冠心病遗传关联

冠状动脉

The correlation was shown with adjustment for age, sex, SBP, DBP, BMI, TC, TG, HDL-C, LDL-C, glucose, smoking, DM, and hypertension status. The rs1333049 GG genotype was as reference.

NIAID Data Ecosystem30

Secondary analysis: results of gene-based replication in FHS for genes containing SNPs associated with CAC in the GENOA discovery cohort.

冠心病遗传关联

基因验证

The number of LD blocks in each gene region used to correct for multiple testing are presented, as well as thresholds for significance in FHS. SNP, single nucleotide polymorphism; Chr, chromosome; Mb,

NIAID Data Ecosystem20

<i>MTHFR</i> C677T genotype frequencies in the CHD group at the type level.

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