Whole genome sequencing of the genome of a newly isolated lytic bacteriophage active against Escherichia coli strains associated with calf escherichiosis.
aIndependent cultures of wild type V. cholerae O1 were used to inoculate 103 CFU per microcosm containing pond water and chitin as a sole nutrient source.bICP1 was simultaneously added at an MOI = 0.0
This study presents a continuous evolution platform that induced multiple single nucleotide polymorphisms in multiple hot-spot regions of the phage genome, enhancing bacterial host range and suppressi