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Overexpression of RAB44 in two bladder cell lines inhibited apoptosis and promoted EMT

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA701530
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To investigate the functional effects of RAB44 ectopic expression in tumorigenesis, we over expressed RAB44 in two immortalized but non-tumorigenic bladder cell lines, UROtsa and SV-HUC-1, using lentivirus infection strategy. RNA-Seq data are consistent with flow cytometry and fluorescence microscopy that apoptosis is inhibited and Epithelial-to-Mesenchymal Transition is promoted when RAB44 is overexpressed.
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2021-02-12
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