FACTOR XIA IN COMPLEX WITH THE INHIBITOR ethyl (2R,7S)-7-({(2E)-3-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]prop-2-enoyl}amino)-15-[(methoxycarbonyl)amino]-2,3,4,5,6,7-hexahydro-1H-12,8-(metheno)-1,9-benzodiazacyclotetradecine-2-carboxylate
收藏Protein Data Bank Japan2026-02-18 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5qty
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FACTOR XIA IN COMPLEX WITH THE INHIBITOR ethyl (2R,7S)-7-({(2E)-3-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]prop-2-enoyl}amino)-15-[(methoxycarbonyl)amino]-2,3,4,5,6,7-hexahydro-1H-12,8-(metheno)-1,9-benzodiazacyclotetradecine-2-carboxylate Descriptor: 1,2-ETHANEDIOL, Coagulation factor XI, SULFATE ION, ... Authors: Sheriff, S. Deposit date: 2019-11-13 Release date: 2020-01-29 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Orally bioavailable amine-linked macrocyclic inhibitors of factor XIa. Bioorg.Med.Chem.Lett., 30, 2020
创建时间：
2019-11-13
