Male and female curves were analyzed independently owing to pronounced sex differences. Permutation tests were performed using the CompareGrowthCurves function in the statmod R package. (TXT)
Mice were chow-fed, 10-week-old B6 (WT) males, intravenously injected with ADOX vectors expressing GFP or Ildr2. Measurements were taken at 10 days p.t. (following either a 24-hr fast “Fasted” or foll
Oxygen consumption (VO2), carbon dioxide production (VCO2), RQ ratio, spontaneous physical activity, calculated glucose and lipid oxidation rate, and energy production rate were measured while mice we