Biologic Treatment Outcomes in Refractory Eosinophilic Fasciitis: A Systematic Review of Published Reports

Eosinophilic fasciitis (EF) is a rare disorder characterized by soft tissue edema, skin erythema and induration, which may progress to fascial fibrosis, and predominantly affects the arms, legs and trunk. While oral corticosteroids are first line therapy, biologic therapies have been reported in refractory EF. This systematic review summarizes treatment outcomes of biologic therapies for EF.