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Tet1 is a tumor suppressor of hematopoietic maligancy. Tet1 is a tumor suppressor of hematopoietic maligancy

NIAID Data Ecosystem2026-03-08 收录

造血系统肿瘤

Tet1肿瘤抑制机制

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA275551 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2015-02-16

基因表达分析

造血系统肿瘤

To decipher molecular targets responsible for c-Kit mutant D816V mediated hematopoietic malignancy, we employed whole genome microarray expression profiling as a discovery platform to identify importa

NIAID Data Ecosystem80

DataSet_hematopoietic_malignancy-EXON - samples

造血系统肿瘤

基因组测序

Rare cancer sequencing data of 87 runs in tumor/control pairs, which were uploaded to umbrella studies. The sequencing was always pairedEGA dataset EGAD00001008882

NIAID Data Ecosystem40

Characterization of inbred strains for naturally occurring hematopoietic neoplasms.

造血系统肿瘤

近交系小鼠表型分析

Characterization of inbred strains for naturally occurring hematopoietic neoplasms.

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BRCA1 and TP53 Co-Deficiency Causes a PARP-inhibitor Sensitive Erythroproliferative Neoplasm

造血系统肿瘤

PARP抑制剂敏感性

Mutations in the BRCA1 tumor suppressor gene, such as 5382insC (BRCA15382insC), give carriers an increased risk for breast, ovarian, prostate and pancreatic cancers. We have previously reported that,

NIAID Data Ecosystem40

Inhibition of the PI3K/Akt/GSK3 Pathway Downstream of BCR/ABL, Jak2-V617F, or FLT3-ITD Downregulates DNA Damage-Induced Chk1 Activation as Well as G2/M Arrest and Prominently Enhances Induction of Apoptosis

造血系统肿瘤

化疗耐药性

Constitutively-activated tyrosine kinase mutants, such as BCR/ABL, FLT3-ITD, and Jak2-V617F, play important roles in pathogenesis of hematopoietic malignancies and in acquisition of therapy resistance

NIAID Data Ecosystem40

Tet1 is a tumor suppressor of hematopoietic maligancy. Tet1 is a tumor suppressor of hematopoietic maligancy

资源简介：

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