Crystal structure of the R132H mutant of IDH1 bound to AG-120
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Crystal structure of the R132H mutant of IDH1 bound to AG-120 Descriptor: Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ivosidenib Authors: Lu, J, Abeywickrema, P, Heo, M.R, Parthasarathy, G, McCoy, M, Soisson, S.M. Deposit date: 2023-06-20 Release date: 2024-08-28 Last modified: 2025-03-12 Method: X-RAY DIFFRACTION (2.053 Å) Cite: Biostructural, biochemical and biophysical studies of mutant IDH1. Nat Commun, 15, 2024
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2023-06-20
