Crystal Structure of SETD2 bound to Compound 2
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Crystal Structure of SETD2 bound to Compound 2 Descriptor: BETA-MERCAPTOETHANOL, Histone-lysine N-methyltransferase SETD2, N-[(1r,4r)-4-(beta-alanylamino)cyclohexyl]-7-methyl-1H-indole-2-carboxamide, ... Authors: Farrow, N.A, Boriack-Sjodin, P. Deposit date: 2021-03-09 Release date: 2021-09-22 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Discovery of a First-in-Class Inhibitor of the Histone Methyltransferase SETD2 Suitable for Preclinical Studies. Acs Med.Chem.Lett., 12, 2021
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2021-03-09
