Hypoxic training in thoroughbred horses

The aim of this study was to examine the effects of six weeks of normobaric hypoxic training when the fraction of oxygen in the inspired air (FiO₂) was reduced from 0.21 to 0.15, simulating the partial pressure of oxygen at an altitude of approximately 3000 m, on mRNA levels at rest for a number of selected enzymes and regulatory factors in aerobic and glycolytic energy pathways in Thoroughbred horses. In this study we investigated the transcriptional changes of selected genes which have been shown to be linked to aerobic performance in an endeavour to provide more insight into the potential impact of the hypoxic stimuli on Thoroughbred horses.