Additional file 5 of SRSF3 and SRSF7 modulate 3′UTR length through suppression or activation of proximal polyadenylation sites and regulation of CFIm levels
We adapted tag-based methods in conjunction with SOLiD and Illumina deep sequencing platforms to determine the precise 5â and 3â ends of VACV early mRNAs and map the transcription start sites (TSS
List of head-specific extended genes. The table provides the genes for which the weighted terminal 3ⲠUTR length is more than 100 bp longer in head compared to both ovary and female carcass. (XLS 4
The main goal of this proposal is to build a comprehensive understanding of a new layer of eukaryotic 3’-end precursor-mRNA processing, with focus on the Cleavage Stimulation Factor (CStF) complex. Th
The nuclear cap-binding complex (CBC) stimulates multiple steps in several RNA maturation pathways, but how it functions in humans is incompletely understood. For small capped RNAs like pre-snRNAs, th
The post-transcriptional fate of messenger RNAs (mRNAs) is largely dictated by their 3' untranslated regions (3'UTRs), which are defined by cleavage and polyadenylation (CPA) of pre-mRNAs. We used pol
