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治疗抑郁症的中药组合物配方、制备工艺、动物实验数据集

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贵州省数据知识产权登记平台2025-10-11 更新2025-10-12 收录
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https://gzdipp.gzsis.cn:12020/noticeDetail?id=1393&type=1
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资源简介:
1、数据采集:依据中医药理论结合抑郁症的诱因及其症状、药材药性药味及主治功能等对中药材进行筛选,采集药材品种、药材用量、加工工序、工艺名称、处理方式、工艺指标、工艺参数、实验条件、实验结果等; 2、数据处理: (1)对不同配方、工艺所得制剂的药效学实验等验证,经数据清洗(如剔除误差)、数据分析(如主成分分析法等),形成配方及制备工艺数据集,获得药材品种、药材用量、加工工序、处理方式、工艺名称、工艺指标、工艺参数等。 (2)基于动物药效学实验和毒理实验,经数据清洗、统计及分析等,形成药效实验关键数据集,获得用药剂量、动物数、给药次数、给药周期等。 3、数据应用:基于该数据集适用于药品领域中抑郁症治疗药物的研发、生产、临床运用场景,有利于提高药物研发及生产效率、临床疗效预测精准性。

1. Data Collection: Screen traditional Chinese medicinal materials based on Traditional Chinese Medicine (TCM) theory, combined with the inducements and clinical symptoms of depression, as well as the properties, flavours and therapeutic indications of medicinal materials. Collect relevant information including medicinal material varieties, dosage, processing procedures, process names, treatment methods, process indicators, process parameters, experimental conditions and experimental results. 2. Data Processing: (1) Validate pharmacodynamic experiments of preparations prepared with different formulas and processes. After data cleaning (e.g., removing erroneous data) and data analysis (e.g., Principal Component Analysis, PCA), establish a formula and preparation process dataset, and obtain information such as medicinal material varieties, dosage, processing procedures, treatment methods, process names, process indicators and process parameters. (2) Based on animal pharmacodynamic experiments and toxicological experiments, through data cleaning, statistical analysis and other processing, establish a key pharmacodynamic experiment dataset, and obtain information such as medication dosage, number of test animals, administration times and administration cycle. 3. Data Application: This dataset is applicable to the R&D, production and clinical application scenarios of antidepressant drugs in the pharmaceutical field, which can effectively improve the efficiency of drug R&D and production, as well as the accuracy of clinical efficacy prediction.
提供机构:
国药集团同济堂(贵州)制药有限公司
创建时间:
2025-10-10
搜集汇总
数据集介绍
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背景与挑战
背景概述
该数据集聚焦于治疗抑郁症的中药组合物,包含配方、制备工艺和动物实验数据,规模为106KB,无定期更新。它适用于药物研发、生产和临床转化场景,通过中医药理论筛选药材并经过数据清洗分析,为药品有效性、安全性及质量稳定性提供支撑。
以上内容由遇见数据集搜集并总结生成
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