(A) IFN-competent A549 cells were treated with 100 IU/ml IFN-α prior to (-4 h, -2 h) or after (2 h, 4 h, 6 h, 8 h) or at the time point of infection (0 h) with the DENV2 strain 16681 at a MOI of 10 TC
To explore the molecular mechanism of Cnpy3 in the treatment of DENVs infection, transcriptome analysis was performed on the brains of suckling mice at two time points of DENVs infection after LNP-C
The time points at which the gene (gene ID, the gene name and the cDNA shown) are significantly differentially expressed between the two strains are shown. The fold changes of expression with respect
Dengue virus infects target cells by attaching to a cell surface receptor through the envelope (E) glycoprotein, located on the surface of the viral membrane. On Vero and BHK cells, heparan sulfate (H
