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The elusive function of metallothioneins

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PubMed Central1998-07-21 更新2026-05-02 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC33872/
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资源简介:
Biochemistry and genetics are both required to elucidate the function of macromolecules. There is no question that metallothioneins (MTs) have unique biochemical properties, but genetic experiments have not substantiated the importance of MTs under physiological conditions. Even after thousands of studies describing the structure, biochemical characteristics, tissue distribution, induction, and consequences of genetic disruption and deliberate overexpression, the evolutionary forces that led to the initial appearance, gene duplications, and nearly ubiquitous expression of MTs remain enigmatic.
提供机构:
National Academy of Sciences
创建时间:
1998-07-21
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