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Chromatin profiling following SWI/SNF inhibition in neuroblastoma cells [ChIP-seq]

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NIAID Data Ecosystem2026-05-01 收录
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To assess the genome-wide effects of SWI/SNF activity in MYCN-amplified neuroblastoma cells, we performed ChIP-seq in IMR-32 cells treated with either DMSO or the SWI/SNF inhibitor BRM014. Pronounced loss of chromatin occupancy was observed for members of the neuroblastoma core regulatory circuitry within 1 hour. ChIP-seq in neuroblastoma cells

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2024-01-17
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