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Wolfram Syndrome RNA-seq

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Purpose: The goals of this study are to compare NGS-derived retinal transcriptome profiling (RNA-seq) from WT and Wfs1-/- mices. Methods: Retinal mRNA profiles of 240-day-old wild-type (WT) and retina Wolframin knockout (Wfs1-/-) mice were generated by deep sequencing, in triplicate, using Illumina NovaSeq 6000. The sequence reads that passed quality filters were aligned to reference genome Retinal mRNA profiles of 240-day old wild type (WT) and Wfs1-/- mice

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