FLEXOME software suite

This protein analysis software identifies rigid and flexible regions in a protein crystal structure; identifies easy directions of motion for the structure; and explores the motion of the structure along these directions. This generates a set of flexible variations on the starting structure, suggestive of the range of variation it will explore naturally in solution.

该蛋白质分析软件能够识别蛋白质晶体结构中的刚性和柔性区域；确定结构的易动方向；并沿着这些方向探索结构的运动。通过这种方式，软件生成了一组基于起始结构的柔性变体，暗示了其在溶液中自然探索的变异范围。