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Gene expression analysis of human iPSC generated from pathogenic LRRK2 (G2019S) mutation bearing patients

ChEBI2012-10-17 更新2026-07-21 收录

帕金森病细胞模型

LRRK2突变机制研究

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-33298 数据链接链接失效反馈

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资源简介：

Gene expression analysis of human iPSC generated from pathogenic LRRK2 (G2019S) mutation bearing patients

应用场景：

创建时间：

2012-10-17

帕金森病细胞模型

基因表达分析

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series from fibroblasts, iPSCs and neurons with four copies of SNCA, and equivalent cell lines from an u

NIAID Data Ecosystem70

An iPSC Model of Early Onset Parkinson's Disease

帕金森病细胞模型

神经退行性疾病药物

Early onset Parkinson’s Disease (onset <50 years) accounts for between 10-20 percent of all patients. While some of these cases are associated with specific mutations, the majority are sporadic where

NIAID Data Ecosystem60

Phenotypic characterization of retinoic acid differentiated SH-SY5Y cells by transcriptional profiling

帕金森病细胞模型

多巴胺能神经元

Multiple genetic and environmental factors play a role in the development and progression of Parkinson’s disease (PD). The main neuropathological hallmark of PD is the degeneration of dopaminergic (DA

NIAID Data Ecosystem30

Rotenone Susceptibility Phenotype in Olfactory Derived Patient Cells as a Model of Idiopathic Parkinson’s Disease

帕金森病细胞模型

线粒体功能障碍

Parkinson’s disease is a complex age-related neurodegenerative disorder. Approximately 90% of Parkinson’s disease cases are idiopathic, of unknown origin. The aetiology of Parkinson’s disease is not f

NIAID Data Ecosystem70

Table_1_Transcriptome and Proteome Analysis in LUHMES Cells Overexpressing Alpha-Synuclein.XLSX

帕金森病细胞模型

蛋白质组-转录组关联分析

LUHMES cells share many characteristics with human dopaminergic neurons in the substantia nigra, the cells, the demise of which is responsible for the motor symptoms in Parkinson's disease (PD). LUHME

NIAID Data Ecosystem40

Gene expression analysis of human iPSC generated from pathogenic LRRK2 (G2019S) mutation bearing patients

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