Protein quality control by MARCH6/TRC8
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https://www.omicsdi.org/dataset/pride/PXD008955
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资源简介：
Forward genetic screens in human cells we find that the proteasome-mediated degradation of the soluble misfolded reporter, mCherry-CL1, involves two ER-resident E3 ligases, MARCH6 and TRC8. To identify a more physiological correlate we used quantitative mass spectrometry and found that TRC8 and MARCH6 depletion altered the turnover of the tail-anchored protein Heme-Oxygenase-1 (HO-1).
创建时间：
2018-04-18
